ea0011p870 | Thyroid | ECE2006
Cosci B
, Altea M
, Castagna M
, Romei C
, Piampiani P
, Vivaldi A
, Ciampi R
, Faviana P
, Basolo F
, Pinchera A
, Elisei R
Mutations in the RET proto-oncogene are responsible for multiple endocrine neoplasia type II. Somatic RET mutations were described in 50% of medullary thyroid carcinoma (MTC). We describe here a novel germline mutation of the RET gene detected in an apparentely sporadic MTC.The index case was a 67 years old patient who arrived at our observation for a bilateral laterocervical linfoadenopathy. The patient was clinically evaluated for thyroid function and ...